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Editor's Correspondence
January 25, 1999

Failure of Alcohol Reduction to Lower Blood Pressure in the PATHS Trial

Arch Intern Med. 1999;159(2):195-196. doi:

In reply

We thank Bulpitt and Shipley for their comments concerning the results from the Prevention and Treatment of Hypertension Study (PATHS),1 a trial of 641 moderate to heavy drinkers with above normal to mildly elevated diastolic blood pressure, randomized to an intervention to lower alcohol intake or to a control group. They suggest that we were unable to confirm a consistent reduction in (diastolic) blood pressure because there may not be a relationship between alcohol and blood pressure at levels below 500 g/wk, which is equivalent to 5.1 drinks per day as we calculated it (14 g per drink).2