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Editor's Correspondence
October 25, 1999

Influence of Coinfection With Hepatitis Viruses on Human Immunodeficiency Plasma Viral Load

Arch Intern Med. 1999;159(19):2367-2368. doi:

About 40% of patients infected with human immunodeficiency virus (HIV) are coinfected with hepatitis C virus (HCV), mainly because both viruses share the same routes of transmission. It has been demonstrated by several studies that HIV infection causes a more rapid progression of chronic hepatitis C to cirrhosis and liver failure.1,2 In agreement with that, increased degrees of hepatitis C viremia have been observed in coinfected patients.1,3 Among the mechanisms potentially implicated, interaction between the viruses and the immunosuppressive state induced by HIV infection have been suggested.3,4