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Editor's Correspondence
February 28, 2000

Celecoxib-Induced Acute Pancreatitis and Hepatitis: A Case Report

Author Affiliations

Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000

Arch Intern Med. 2000;160(4):553-554. doi:

Celecoxib (Celebrex; Searle & Co Pharmaceuticals, Skokie, Ill, and Pfizer Inc, New York, NY) is a new and popular nonsteroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase 2.1 It is approved for the treatment of both rheumatoid arthritis and osteoarthritis. Recognized adverse reactions include gastrointestinal hemorrhage, hepatitis, abdominal pain, and diarrhea. It should not be administered to patients with allergies to sulfa drugs. Acute pancreatitis has not been reported with the use of celecoxib.

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