Cases of thrombotic thrombocytopenic purpura (TTP) have been reported in patients who are infected with the human immunodeficiency virus (HIV).1,2 Recently, manifestations resembling TTP have been reported in HIV-infected patients who were treated with high-dose valacyclovir hydrochloride, 8 g/d.3 We report here a case of TTP in an HIV-infected patient who was treated with a lower dose of valacyclovir.
Rivaud E, Massiani M, Vincent F, Azoulay E, Couderc L. Valacyclovir Hydrochloride Therapy and Thrombotic Thrombocytopenic Purpura in a HIV-Infected Patient. Arch Intern Med. 2000;160(11):1705–1706. doi:
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