Cerebrospinal meningitis with a prolonged course presents two varieties. In one we observe only recurrences or episodic meningeal manifestations. Here the patient during the intervals appears to be in perfect health. Nevertheless, suddenly or insidiously the symptoms return either in a slight or grave form. The intervals may last either a few days or a few weeks.
The other variety which is the subject of the present contribution, concerns cases of cerebrospinal meningitis the evolution of which is continuous. While in the literature are mentioned a few such isolated cases under different captions, nevertheless their chief characteristic features have not been sufficiently emphasized by various authors with the exception of Robert Debré, pupil of Netter. In 1845 Tungel1 for the first time speaks of disturbances in the brain tissue proper in the course of a prolonged case of cerebrospinal meningitis. The next two earliest records we find by Rilliet2 and
GORDON A. THE CHRONIC FORM OF MENINGOCOCCUS MENINGITIS. Arch Intern Med (Chic). 1919;23(2):150–157. doi:10.1001/archinte.1919.00090190020002
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