We have studied the blood sugar levels in 127 cases of diabetes, fifty-six males and seventy-one females, making in all 1,106 blood sugar determinations. In our study of the renal threshold for sugar in diabetes, we found no constant blood sugar level for the appearance of urinary sugar. Hopkins1 says that there is no constant renal threshold. Hamman and Hirschman2 found the normal threshold between 0.17 and 0.18 per cent., and our own findings would seem to corroborate this. In diabetes, however, we may find a lowering or an elevation of the threshold. In the former case, the blood sugar level may be very slightly lowered or may approximate normal values. We now have under observation several patients who persistently show reducing substances in the urine accompanied by low blood sugar values. Some of these cases may prove to be cases of alimentary glycosuria or renal diabetes. We
WILLIAMS JR. THE CLINICAL SIGNIFICANCE OF BLOOD SUGAR IN DIABETES MELLITUS. Arch Intern Med (Chic). 1919;23(5):546–558. doi:10.1001/archinte.1919.00090220011002
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