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Article
October 1919

THE CONTROL OF ACIDOSIS IN THE TREATMENT OF DIABETES

Author Affiliations

NEW YORK

From the Hospital of the Rockefeller Institute for Medical Research, New York.

Arch Intern Med (Chic). 1919;24(4):445-457. doi:10.1001/archinte.1919.00090270091009
Abstract

INTRODUCTION  During the past five years marked advances have been made in the treatment of diabetes, due largely to the introduction by Allen of the "fasting method." In the practical application of this method of treatment the patient is fasted until glycosuria disappears; and subsequent to the initial fast, fasting is employed to such an extent as is necessary to aid in keeping the patient free from glycosuria. In other words, the most important and significant sign or symptom by which the therapeutic regime is regulated is the presence or absence of sugar in the urine. Allen, however, has emphasized the fact that in diabetes a disturbance of the entire metabolic mechanism of the body is present, and that the presence or absence of glycosuria at any given time is but a crude test of the state of that function, though practically it is the best test available. In the

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