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January 1922


Author Affiliations


From the Magee Pathological Institute, Mercy Hospital, Pittsburgh.

Arch Intern Med (Chic). 1922;29(1):131-140. doi:10.1001/archinte.1922.00110010136009

The pioneer investigators of the etiologic factors and pathologic processes in arteries have, in a large measure, centered their attention on the more imminent problems of the subject, so that today a wealth of information has been contributed to our knowledge of syphilis and sclerosis of vascular channels. Again, the results of more acute bacterial invasion on the wall of both the aorta and the peripheral arterial tree, as well as the various manifestations of the same organisms on the different arterial systems of the tree, have been studied carefully by others. This is especially true in the case of acute rheumatic fever, with or without an attending acute or subacute bacterial endocarditis, and, to a lesser extent, in other acute affections, notably scarlet fever, septicemia, typhoid fever and pneumonia. Thus our understanding of the modus operandi of acute bacterial invasion of the peripheral arteries has broadened. It is only

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