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June 1922


Arch Intern Med (Chic). 1922;29(6):868-869. doi:10.1001/archinte.1922.00110060162014

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This octavo volume of 310 pages embodies a report of work conducted during the late war under the author's direction by the section on Intermediary Metabolism of the Medical Division of the Chemical Warfare Service, organized originally by the Bureau of Mines. The work of this section consisted largely in exposing dogs during single or repeated periods of different time lengths to chlorin, phosgene or chlorpicrin in known and varying concentrations. Thorough and systematic examinations were made of the gassed animals under exactly specified conditions as to the clinical symptoms and their course, of the mor

phologic and volume changes in the tissues and blood, the chemical changes in the blood and urine, the respiratory function, the acid base balance, etc. The findings are tabulated in detail together with the writer's analysis and interpretation. Having established a standard for control, experiments were performed with different therapeutic procedures.

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