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September 1922


Author Affiliations


Arch Intern Med (Chic). 1922;30(3):343-354. doi:10.1001/archinte.1922.00110090076005

Bronchospirochetosis was first discovered by Castellani in 1905 in patients seen in Ceylon. The spirochetes which he found to be the causative agents of the disease were described by him in 1907 under the name of Spirochaeta bronchialis. About the same time Bertarelli and Volpina noted spirochetes in the sputum of persons suffering from heart disease, while Rona found similar organisms in cases of pulmonary gangrene. Since then instances have been reported from many localities. Lurie1 recorded the presence of the disease in China, although the first and only published case history I have been able to find is that of Lee2 from Wusih.

In view of the widespread incidence of bronchospirochetosis in Europe, North America and in parts of Asia (Ceylon, Philippines and Siam), I have been surprised to find records of the infection almost wholly lacking for China. In collaboration with Dr. C. McA. Wassell I have had

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