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November 1923


Author Affiliations


Arch Intern Med (Chic). 1923;32(5):663-671. doi:10.1001/archinte.1923.00110230019002

Gastric and duodenal ulcer are frequently discussed under the heading of "peptic" ulcer, and there is no doubt that many of their hypothetical etiologic factors and clinical manifestations bring them into close relationship. The use of this general term, however, is by no means always advisable and leads to deductions that are not only confusing but erroneous. Statistics have been published under such a heading concerning the variations in the secretory and motor activities of the stomach, no attempt being made to discriminate between the two types of ulcer. Information thus obtained is valueless, for in these respects gastric and duodenal ulcers are markedly dissimilar. There is much evidence to support Hurst's1 view that the motor activities of the stomach differ in the two conditions.

Since the introduction and widespread adoption of the fractional method of analysis of the gastric contents, it has become necessary to modify and even to