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Article
February 1924

ALIMENTARY LEUKOCYTOSIS IN VARIOUS PATHOLOGIC CONDITIONS: A FURTHER STUDY IN REFERENCE TO THE CRISE HÉMOCLASIQUE OF WIDAL

Author Affiliations

BROOKLYN

From the Department of Internal Medicine, Long Island College Hospital, Brooklyn, N. Y.

Arch Intern Med (Chic). 1924;33(2):210-216. doi:10.1001/archinte.1924.00110260056004
Abstract

This report is based on the use of the Widal test for hepatic insufficiency in a group of fifty patients with miscellaneous conditions. It represents the second phase of a study suggested to me by the statement by Widal, Abrami and Iancovesco1 in 1920 that leukopenia following a standard protein meal is to be regarded as a delicate test for insufficiency of the liver.

The technic of the test proposed by Widal is simple. The subject to be examined abstains completely from food for a period of at least five hours preceding the test. This detail is of great importance, as the ingestion of nitrogenous food, no matter how small the amount, interferes greatly with the reaction. A leukocyte count is made, and then the subject drinks 200 gm. of milk (a glass of milk, the exact amount not being essential). Subsequently, the leukocytes are counted at intervals of twenty

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