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August 1924


Author Affiliations


From the Department of Pathology, Harvard Medical School, and the Pathological Laboratory, Long Island Hospital.

Arch Intern Med (Chic). 1924;34(2):191-205. doi:10.1001/archinte.1924.00120020057007

The histogenesis and classification of primary malignant tumors of the pleura has been the subject of much controversy. Opinion has been divided as to whether they should fall under the class of carcinoma or sarcoma, or be placed in a separate group of endothelioma. The nomenclature of each author has been based rather on his opinion of the type of cell from which the tumor has arisen than on the grounds of the histologic appearance of the growth. Against an embryologic classification of tumors, Ewing1 urges that we consider the behavior of neoplastic cells as being influenced more by the acquired characters of the cells of origin than by their embryologic derivation. He states that oncology is not a department of embryology, but a separate chapter in the biology of the cell. Similarly, Adler2 believes that the structure of a tumor is not dependent on its morphologic relation to the

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