There is a difference, at least in degree, between obesity and overweight. Overweight usually results from overfeeding, sedentary habits or a combination of both. Certain cases of obesity unquestionably follow the same causes, but just as unquestionably other cases of obesity are seen which show neither excessive food intake nor lessened energy expense. In such persons the tendency to accumulate and deposit fat seems to be entirely independent of any of the usual causes of increased weight. Both overeating and underexercise are common faults of mankind, yet excessive obesity is comparatively rare. On the other hand, one sees a fairly large number of healthy but thin persons whose food intake is in excess of their calculated caloric requirements, yet who cannot gain weight under any circumstances. The conclusion seems almost inevitable that the maintenance of body weight may be practically independent of the caloric balance, and that obesity may
STROUSE S, DYE M. STUDIES ON THE METABOLISM OF OBESITY: I. THE RELATION BETWEEN FOOD INTAKE AND BODY WEIGHT IN SOME OBESE PERSONS. Arch Intern Med (Chic). 1924;34(3):267–274. doi:10.1001/archinte.1924.00120030002001
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