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Article
February 1925

A QUANTITATIVE TEST OF DIGESTIVE PANCREATIC ACTIVITY, EASILY APPLIED CLINICALLY: TESTS FOR VOLUME OF PANCREATIC JUICE AND BILE SECRETIONS

Arch Intern Med (Chic). 1925;35(2):162-176. doi:10.1001/archinte.1925.00120080014002
Abstract

The value of some clinical method of estimating the digestive activity of pancreatic juice is apparent. Extraction of small portions of the duodenal contents and the testing of the return to note the presence of enzymes have been devised, but all of the methods are only qualitative, and the admixture action of the enzymes takes place outside the body instead of in vivo. For these reasons, they have not been popular. A method that called for the use of tubes filled with various substances had been suggested,1 in which the element of error is too great for clinical purposes. Another method, much more accurate but quite impossible as a routine clinical procedure, has been devised2 in which the three enzymes are estimated. The oil regurgitation method of Boldyreff and Volhard is not practical. The best work thus far reported has been done by Crohn,3 and acknowledgment is made of its

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