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Article
November 1925

DEFECTS OF MEMBRANOUS BONES, EXOPHTHALMOS AND DIABETES INSIPIDUS: REPORT OF A CASE WITH NECROPSY

Author Affiliations

OMAHA

From the department of clinical investigation, University of Nebraska College of Medicine.

Arch Intern Med (Chic). 1925;36(5):650-666. doi:10.1001/archinte.1925.00120170059005
Abstract

In 1919, Christian,1 under the title, "Defects in Membranous Bones, Exophthalmos and Diabetes Insipidus, an Unusual Syndrome of Dyspituitarism," reported a case presenting this syndrome and cited two similar cases previously described by Schüller.2 Three other cases have since been reported by Hand3 and one by Grosh and Stifel,4 making seven cases in all reported to date. The following case was deemed worthy of a detailed report because of the unusually widespread osseous dissolution present, because of the rarity of the condition, and finally to record a complete postmortem study of this strange disease complex.

REPORT OF CASE 

History.  —C. J., a boy, aged nine years, came to us, Feb. 15, 1923, seeking relief from excessive thirst and frequent urination.The father, mother, one sister and one brother were living and well. The mother had had no miscarriages. One brother died when five months old of cholera infantum.The patient

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