In 1919, Christian,1 under the title, "Defects in Membranous Bones, Exophthalmos and Diabetes Insipidus, an Unusual Syndrome of Dyspituitarism," reported a case presenting this syndrome and cited two similar cases previously described by Schüller.2 Three other cases have since been reported by Hand3 and one by Grosh and Stifel,4 making seven cases in all reported to date. The following case was deemed worthy of a detailed report because of the unusually widespread osseous dissolution present, because of the rarity of the condition, and finally to record a complete postmortem study of this strange disease complex.
REPORT OF CASE
—C. J., a boy, aged nine years, came to us, Feb. 15, 1923, seeking relief from excessive thirst and frequent urination.The father, mother, one sister and one brother were living and well. The mother had had no miscarriages. One brother died when five months old of cholera infantum.The patient
THOMPSON CQ, KEEGAN JJ, DUNN AD. DEFECTS OF MEMBRANOUS BONES, EXOPHTHALMOS AND DIABETES INSIPIDUS: REPORT OF A CASE WITH NECROPSY. Arch Intern Med (Chic). 1925;36(5):650–666. doi:https://doi.org/10.1001/archinte.1925.00120170059005
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