This is a preliminary report of the use of sodoku in the treatment of general paralysis. The series consists of twelve paretic patients who were inoculated with Spirochaeta morsus-muris, the etiologic agent of sodoku. This work was undertaken in an attempt to improve on the malarial method which has been used for eight or nine years in the treatment of general paralysis. It therefore seems advisable to preface the report of our investigations with an account of the treatment of general paralysis by malaria and other febrile producing methods.
In 1917 von Jauregg1 introduced the malarial method. Since that time it has been quite generally utilized in most of the countries of Europe and also in the United States, the results reported being extremely favorable. The method usually consists of inoculating a patient with malarial blood, which leads to the development of malarial paroxysms. The patient is generally allowed to
SOLOMON HC, BERK A, THEILER M, CLAY CL. THE USE OF SODOKU IN THE TREATMENT OF GENERAL PARALYSISA PRELIMINARY REPORT. Arch Intern Med (Chic). 1926;38(3):391–404. doi:10.1001/archinte.1926.00120270114010
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