The difference in the erythrocyte count of the first drop of blood as compared with subsequent drops of blood issuing from the lanced finger of a normal person has been described in the preceding article.1 The reversal of this difference, observed in patients with chronic arthritis, lends special interest to this subject and suggests the existence of an abnormal peripheral circulatory condition in these patients. For this reason it seemed desirable to check the observations of Peirce and Pemberton independently and, if possible, by other methods. This was particularly appropriate in view of the fact that many of the differences in blood count reported by them are of about the same magnitude as is the error of the method used in the red cell count.
In the hope of checking up the work by entirely independent means, the problem was attacked in various ways. Differences in the red cell content
CROUTER CY, CAJORI FA. THE RED CELL COUNT IN ARTHRITIS: SECOND PAPER. Arch Intern Med (Chic). 1927;39(3):429–432. doi:10.1001/archinte.1927.00130030114010
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