At the present time a large number of histories are being reviewed of patients who came to the Mayo Clinic complaining of gastro-intestinal hemorrhage. In this study only benign gastroduodenal lesions are included. In most of the series of cases that came to operation ulcers, gastric, duodenal or gastrojejunal, were found. There was, however, a surprisingly large number of cases in which a definite ulceration was not demonstrable at the operating table. In some of these, there were gastric, duodenal or esophageal varices; in a few, there was evidence of marked hepatitis; in others, splenomegaly or cirrhosis of the liver, and in a certain number it was assumed that a blood dyscrasia was responsible for the hemorrhages. Again, in other instances, some pathologic conditions of the gallbladder or appendix were found, and it was assumed that the condition was probably one commonly termed "gallbladder bleeding" or "appendiceal bleeding."
RIVERS AB. HEMORRHAGIC FOCAL GASTRODUODENAL LESIONS: PRELIMINARY REPORT OF THREE CASES. Arch Intern Med (Chic). 1927;39(4):564–570. doi:10.1001/archinte.1927.00130040102009
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