The combination of diabetes and Addison's disease appears from the literature to be of extremely rare occurrence. Heller1 found this association only once in 800 cases of Addison's disease reviewed by him. Although there are five cases in the entire literature in which the authors state that the patients have had diabetes in conjunction with Addison's disease, the diagnosis in every one of these cases may be questioned. The only evidences of diabetes in the patient referred to by Heller were somnolency and a strongly positive reaction for acetone in the urine. Nothnagel,2 who originally reported this case, referred to it merely as one of Addison's disease with severe cerebral manifestations. Of the four remaining cases, certainly that of Rabé3 and possibly that of West4 were instances of tuberculosis of the suprarenal glands with hemochromatosis and glycosuria. In the former case this diagnosis was proved by pathologic studies. In West's
ARNETT JH. ADDISON'S DISEASE AND DIABETES MELLITUS OCCURRING SIMULTANEOUSLY: REPORT OF A CASE. Arch Intern Med (Chic). 1927;39(5):698–704. doi:10.1001/archinte.1927.00130050095008
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: