While making simultaneous observations on gastric motility (by the balloon method) and on the basal metabolic rate (Kleitman),1 a striking increase in the respiratory rate was manifested during some periods of gastric hunger contractions (fig. 1). The increase was recognized by the subject (F. H.) as accounting for his previous belief that the metabolic rate was increased with hunger contractions. This belief occasioned the investigation but was based mainly on subjective experience, particularly during a thirty-three day fast undertaken some time previously. However, similar subjective experience during earlier fasts had already led to a study of this problem by Dr. Kunde (unpublished work). She made observations on a number of subjects, but did not obtain conclusive evidence of an increase in the basal metabolic rate with increases in gastric motor activity. This observation was confirmed by Kleitman. Kunde, however, did not note the striking increase in the respiratory rate which
HOELZEL F, KLEITMAN N. SOME CONDITIONS AFFECTING SUBJECTIVE AND OBJECTIVE MANIFESTATIONS OF HUNGER: HUNGER SENSATION GIVING RISE TO A MARKED RESPIRATORY CHANGE. Arch Intern Med (Chic). 1927;39(5):710–740. doi:10.1001/archinte.1927.00130050107010
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