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Article
June 1927

STUDIES IN ACROMEGALY: VI. THE DISTURBANCES OF CARBOHYDRATE METABOLISM

Author Affiliations

BOSTON

From the Surgical Clinic of the Peter Bent Brigham Hospital, Boston.

Arch Intern Med (Chic). 1927;39(6):751-779. doi:10.1001/archinte.1927.00130060003001
Abstract

CONTENTS 

  • Introduction

  • Incidence

  • Etiology

  1. A. The neurogenic explanations

  2. B. The endocrine explanation

  3. Thyroid, suprarenals, pancreas and hypophysis

  4. The Relation of the Pancreas to Glycosuria

  5. The Relation of the Hypophysis to Glycosuria

  6. Counteraction of pituitary extracts and insulin

  7. Sugar Tolerance Tests of Acromegalic Patients Without Glycosuria

  8. The Course and Prognosis of Acromegalic Diabetes

  9. The Effect of Operations on Sugar Tolerance in Acromegaly

  1. A. With existent melituria

  2. B. With hyperglycemia in the absence of melituria

  3. Summary and Conclusions

INTRODUCTION  In preceding papers in this series the subject which we here propose to discuss more in detail has already been touched on. It has been stated1 that in our series of 100 personally observed cases of acromegaly one out of four has shown glycosuria, and approximately one out of eight proved to have clinically outspoken diabetes mellitus. It has also been stated, in

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