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This monograph is number 3 in the medical series of the Stanford University publications. It is a study based on the results of 3,000 postmortem examinations performed during the years from 1900 to 1923 by Dr. Ophüls and his associates at the Lane and San Francisco Hospitals at San Francisco. In such autopsies gross and microscopic examinations were made of the viscera as a routine. Bacteriologic examinations were made only in cases in which this seemed to be indicated by the nature of the case. A careful and detailed analysis of these 3,000 cases is presented. This is done chiefly by means of charts, of which there are about sixteen, as well as by numerous short tables. The diseases and lesions are classified and named according to the first edition of the "Standard Nomenclature of Diseases and Pathological Conditions, Injuries and Poisonings" issued by the United States Department of Commerce,