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June 1927

Studies on Acidosis.

Arch Intern Med (Chic). 1927;39(6):891-892. doi:10.1001/archinte.1927.00130060143012

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In the first part of this exhaustive report, Dautrebande discusses fully the modern conception of acidosis as developed by the American, English and Danish physiologists and biochemists (Van Slyke, Y. Henderson, Haldane, Barcroft, Hasselbach and others), and includes an explanation of the physiologic mechanism by which acid-base equilibrium is maintained.

In the second part of the paper, contributed by Labbe and Nepveux, methods for the determination of acid-base equilibrium, both direct and functional, are given and compared from the standpoints of ease of manipulation and of relative value.

The third contribution, by Petren, deals with the pathologic physiology of acid-base equilibrium, and in it are discussed the causes of the acidoses found in emphysema, pulmonary tuberculosis, bronchial asthma, bronchial pneumonia, pneumothorax, morphine administration, diabetes, nephritis, enteritis, cyclic vomiting of children, pregnancy, pernicious vomiting of pregnancy, prolonged fasting, anesthesia, lobar pneumonia, shock (traumatic, infectious and anaphylactic) peptic ulcer, various circulatory disturbances

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