It has been shown that sewage filtrate contains lytic principle of marked activity for most of the gram-negative bacilli found in cases of urinary infections.1 Of seventy-five consecutive cases of urinary infections which I have studied up to the present time, sewage filtrate has lyzed 90 per cent of the strains of bacilli isolated from the catheterized specimens of urine. The activity of the sewage filtrate is marked, either in the first passage or after only one or two passages. A complete report of this phase of the subject will be made after the series has been extended.
Because of the ease with which the lytic principle could be obtained from sewage filtrate for these organisms, and the fact that in the past the chief obstacle to the use of the bacteriophage in urinary infections has been the lack of potent bacteriophage to many of the causativebacilli, the situation appeared
CALDWELL JA. BACTERIOPHAGY IN URINARY INFECTIONS FOLLOWING THE ADMINISTRATION OF THE BACTERIOPHAGE THERAPEUTICALLY. Arch Intern Med (Chic). 1928;41(2):189–197. doi:10.1001/archinte.1928.00130140051002
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