The rise in metabolism due to work is well known.1 Boothby and Sandiford2 found that patients with exophthalmic goiter and adenomatous goiter with hyperthyroidism require nearly twice as much energy for a given piece of work as do normal persons or even patients with other diseases. A comparison of the basal metabolism and the metabolism as influenced by work in a series of fifty subjects is herein reported.
MATERIAL AND TECHNIC
The subjects were of three main groups: (a) normal persons (pupil nurses), thirteen; (b) patients clinically considered subjects of exophthalmic goiter or toxic adenoma, fifteen, and (c) other patients, twenty-two.The basal metabolic rate is determined by indirect calorimetry, measuring the consumption of oxygen. The apparatus is provided with a drum which revolves in eight minutes. During the first five minutes, the technic does not vary from the routine except that explanation is first made of what the subject
SMITH JH. BASAL METABOLISMIII. INFLUENCE OF WORK WITH SPECIAL REFERENCE TO THE THYROID GLAND. Arch Intern Med (Chic). 1928;42(1):47–52. doi:10.1001/archinte.1928.00130190050004
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