Pathogenesis in Relation to Hyperlipoidemia and the Reticulo-Endothelial System CONTENTS
Report of Cases.
Résumé of Cases Showing Christian's Syndrome.
Christian's Syndrome and Xanthomatosis.
Historical Consideration of Xanthoma in Relation to Christian's Syndrome.
General Account General comment of the Symptomologic considerations
Clinical Picture Clinical and symptomologic considerations concerning syndrome
Microscopic and clinical changes
Microscopic changes concerning the syndrome
Study of microscopic changes—conclusions
Hypercholesterinemia and animal experimentation
The reticulo-endothelial system and xanthomatosis
General Comment in Relation to the Syndrome.
Conclusions regarding pathogenesis.
Conditions that should be included as manifestations of a general disturbance of lipoid metabolism.
The nature of the nodular lesions.
Clinical features in general.
Summary and Conclusions.
Xanthoma was first described as a rare disease of the skin. It is still classed as a dermatologic condition, although for a long time it has, in all its many
ROWLAND RS. XANTHOMATOSIS AND THE RETICULOENDOTHELIAL SYSTEM: CORRELATION OF AN UNIDENTIFIED GROUP OF CASES DESCRIBED AS DEFECTS IN MEMBRANOUS BONES, EXOPHTHALMOS AND DIABETES INSIPIDUS (CHRISTIAN'S SYNDROME). Arch Intern Med (Chic). 1928;42(5):611–674. doi:10.1001/archinte.1928.00130220002001
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