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Article
March 1929

PEPTIC ULCER: THE EFFECT OF PARENTERAL INJECTIONS OF PURIFIED MILK PROTEINS ON THE SYMPTOMS AND PROGRESS

Author Affiliations

BALTIMORE

From the Gastro-Intestinal Clinic of the Johns Hopkins University School of Medicine.

Arch Intern Med (Chic). 1929;43(3):299-325. doi:10.1001/archinte.1929.00130260002001
Abstract

This paper appears only as a preliminary report. The results of the study have been so interesting and some of them so conclusive that I could not resist presenting the matter at the present time.

By peptic ulcers I mean those on both sides of the pylorus.

As far as I can discover, the first voluntary administrator of foreign protein in the treatment for peptic ulcer was Gottfried Holler,1 who reported on the matter in 1921.

In 1922, Pribram,2 a surgeon in Bier's Clinic, published his reports on the treatment for peptic ulcers with a crystallized vegetable protein.3 His dosage was gradually increased from 0.2 to 1 cc. His results were more or less similar to those of Holler. Both concluded that this form of treatment was a valuable adjunct to the armamentarium and in many ways was much more reliable than the classic medical treatment of the day. They

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