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Article
April 1929

PERFORATIONS OF THE COLON IN CHRONIC ULCERATIVE COLITIS

Author Affiliations

Fellow in Medicine, The Mayo Foundation; ROCHESTER, MINN.

From the division of medicine, The Mayo Clinic.

Arch Intern Med (Chic). 1929;43(4):483-487. doi:10.1001/archinte.1929.00130270057004
Abstract

The complications and sequelae of chronic ulcerative colitis place it in the category of serious diseases. Chronic ulcerative colitis means a definite disease entity presenting characteristic clinical, proctologic, roentgenologic and pathologic observations. Clinically, it is characterized by exacerbations and remissions, and occasionally by acute fulminating infection. During the active stage of the disease, foul-smelling mucus, pus and blood are discharged from the rectum, often associated with almost intractable diarrhea. The latter depends on the extent of involvement of the colon and the severity of the infections so that the patient may complain of constipation associated with frequent passages of blood and pus, particularly if the lesions involve only the rectum and the rectosigmoid.

Thus, because of few pathognomonic symptoms of chronic ulcerative colitis the disease may be confused with amebiasis, tuberculosis, a malignant condition, typhoid fever and other lesions of the colon. According to Buie,1 however, the disease presents a

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