The complications and sequelae of chronic ulcerative colitis place it in the category of serious diseases. Chronic ulcerative colitis means a definite disease entity presenting characteristic clinical, proctologic, roentgenologic and pathologic observations. Clinically, it is characterized by exacerbations and remissions, and occasionally by acute fulminating infection. During the active stage of the disease, foul-smelling mucus, pus and blood are discharged from the rectum, often associated with almost intractable diarrhea. The latter depends on the extent of involvement of the colon and the severity of the infections so that the patient may complain of constipation associated with frequent passages of blood and pus, particularly if the lesions involve only the rectum and the rectosigmoid.
Thus, because of few pathognomonic symptoms of chronic ulcerative colitis the disease may be confused with amebiasis, tuberculosis, a malignant condition, typhoid fever and other lesions of the colon. According to Buie,1 however, the disease presents a
BARGEN JA, JACOBS MF. PERFORATIONS OF THE COLON IN CHRONIC ULCERATIVE COLITIS. Arch Intern Med (Chic). 1929;43(4):483–487. doi:10.1001/archinte.1929.00130270057004
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: