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July 1929


Author Affiliations


From the Radium Clinic of Beth Israel Hospital. New York.

Arch Intern Med (Chic). 1929;44(1):73-117. doi:10.1001/archinte.1929.00140010076008

A review of the literature shows that toxic adenoma of the thyroid has been considered under a variety of names. Some of these synonyms are:

Enlargement of the thyroid gland in connection with enlargement or palpitation of the heart—Parry1 (1825).

Constitutional iodism—Rilliet2 (1859).

Iodine exophthalmic goiter; iodine Graves' disease—Trousseau3 (1860).

Formes frustes exophthalmic goiter—Trousseau4 (1862); Marie5 (1883).

Secondary Basedow—Gauthier6 (1893); Buschan7 (1894).

Basedowified goter—Marie8 (1897); Struma basedowificata—Kocher9 (1906).

Goiter heart—Kraus10 (1898).

Iodine thyroidism—Breuer11 (1900).

Basedowid—Stern12 (1908-1909).

Toxic nonexophthalmic goiter—Plummer13 (1912).

Toxic adenoma of the thyroid—Plummer14 (1913).

Adenoma with hyperthyroidism—Plummer15 (1916).

Hyperfunctioning adenomatous goiter—Plummer16 (1921).

Iodine hyperthyroidism—Jackson17(1924).

Nodular goiter with hyperthyroidism—Rienhoff18 (1927).

In a recent study of the goiter problem, Aschoff19 stated: "We were able to show that the nodular form was not a kind of hyperplasia or hyperplastic condition, as was then believed, but that we were dealing with a definite tumor formation, namely, adenomata." Do simple adenomas of the