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Article
November 1929

CALCIUM STUDIES: IV. THE CALCIUM CONTENT OF CEREBROSPINAL FLUID

Author Affiliations

PHILADELPHIA

From the Medical Service of Dr. Thomas McCrae and the Department for Diseases of the Chest, Jefferson Hospital.

Arch Intern Med (Chic). 1929;44(5):667-669. doi:10.1001/archinte.1929.00140050044003
Abstract

The calcium content of human cerebrospinal fluid has not been extensively investigated, but the general impression is that it is extremely constant in health and in the great majority of pathologic states. Halverson and Bergeim1 and Pincus and Kramer2 found the spinal fluid of human beings to average about 5 mg. per hundred cubic centimeters. Critchley and O'Flynn3 found it to be 6.2 mg., practically constant at that figure and not varying characteristically in disease, with the exception of a fall in tetany and a rise in Froin's syndrome.

The present study consists of the determination of the calcium content of the cerebrospinal fluid of 240 persons. Sixty-eight may be classed as normal, the remaining 172 suffering with a variety of disorders which may be grouped under six headings: (1) pulmonary tuberculosis in various stages of extent and activity; (2) disturbances of an atopic nature, including bronchial asthma, mucous colitis,

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