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December 1929

Nephritis: Its Problems and Treatment.

Arch Intern Med (Chic). 1929;44(6):909. doi:10.1001/archinte.1929.00140060124016

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This volume contains a critical survey of nephritis and deals concisely with its clinical features and treatment. The author emphasizes the inadequacy of present forms of classification, but suggests that renal lesions of the type under discussion may occur as nephrosis, glomerulonephritis and arteriosclerosis with renal manifestations. He leans toward the conception that nephrosis is a part of a general metabolic disturbance in which the kidney shows only one phase. Infection is considered the most probable cause of glomerulonephritis. The author considers that arteriosclerosis with renal manifestations can best be explained by assuming that the arteriolar involvement antedates the renal changes, and that the nephritis is either a result of the vascular change, or due to the same cause which produces an abnormal condition of the arterioles.

Brief discussion of the more important symptoms is offered. The similarity between uremia and tetany is pointed out, particularly the low calcium content

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