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Article
March 1930

THE RESPONSE OF THE RETICULOCYTES IN SECONDARY ANEMIAS FOLLOWING VARIOUS FORMS OF TREATMENT

Author Affiliations

PEIPING, CHINA

From the Department of Medicine, Peiping Union Medical College.

Arch Intern Med (Chic). 1930;45(3):456-463. doi:10.1001/archinte.1930.00140090139008
Abstract

In recent years, the reticulated erythrocytes in the circulating blood have attracted considerable attention in the study of various anemias. This has been particularly true since Minot and Murphy1 pointed out that when patients with pernicious anemia were fed large amounts of liver there was a rapid increase in the production of hemoglobin, erythrocytes and reticulocytes. The increase in the reticulated red blood cells was taken as evidence of the efficiency of liver treatment, and their appearance in the circulating blood as an indication of an active production of red blood cells. During the past year, we have been interested in the reticulocyte response in the various forms of secondary anemia, following different kinds of treatment, and in this essay we propose to present the results of a study of fifty-three cases.

LITERATURE  Before presenting the details of our studies, we shall summarize rather briefly the present knowledge regarding these

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