A symposium in 1928 on chronic ulcerative colitis in the Harvein Society of London reported in the Lancet, in which such eminent men as French, Tidy, Norbury, Smith, Wakely, Broadbent and Wilcox took part, added nothing to knowledge of the etiology of or treatment for this disease. The participants were convinced of the infectious nature of the disease and advocated irrigations and surgical procedures in the treatment. Later the editor of Lancet commented1 on the unknown etiology of the disease. Therefore, this review seems opportune.
The voluminous literature on the subject of chronic ulcerative colitis is briefly summarized as follows: Wilks and Moxon2 mentioned the disease in 1875 in their lectures on pathologic anatomy. A colored drawing by Cruveilhier,3 including work reported between 1829 and 1842, presents a condition which certainly suggests chronic ulcerative colitis. Allchin, in 1885, exhibited to the London Pathological Society a specimen of a colon from
BARGEN JA. CHRONIC ULCERATIVE COLITIS: A REVIEW OF INVESTIGATIONS ON ETIOLOGY. Arch Intern Med (Chic). 1930;45(4):559–572. doi:10.1001/archinte.1930.00140100081008
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