In spite of the advances in the preparation of potent pollen extracts and in the methods of their administration, there are still patients with hay-fever who get practically no relief from their symptoms following preseasonal treatment. The percentage of patients in this group varies from 5 to 10. All others fall into two classes which are about equal in number; namely, those who get complete relief and those in whom marked relief is obtained.
While the use of filtered air1 in addition for a few hours a day makes complete relief practical for the patients in the partially relieved group, and produces marked relief even in those who were previously in the total failure group, intensive study has shown that many in these two classifications can be transferred to the complete relief group by attention to various factors that have been pointed out before but are not generally stressed.
COHEN MB, RUDOLPH JA. HAY-FEVER: THE IMPORTANCE OF SUBSTANCES OTHER THAN POLLEN IN THE ETIOLOGY; THEIR INFLUENCE ON SEASONAL CURE. Arch Intern Med (Chic). 1930;45(5):742–748. doi:10.1001/archinte.1930.00140110098008
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