The high hemoglobin percentage and increased viscosity1 that have been observed in patients with thrombo-angiitis obliterans for many years suggested the probability that in this disease there was concentration of the blood. Studies of blood volume begun several years ago by one of us tended to confirm this supposition, but the number of cases available for study at that time was too few to permit a definite conclusion to be drawn. The large number of patients with thromboangiitis obliterans who have been drawn to the special clinic established for this disease in the outpatient department of Mount Sinai Hospital has made available the clinical material for a more comprehensive study. From the data collected certain conclusions can now be drawn. This paper will deal only with the question of the amount of total blood and plasma in this disease.
The dye method for determining the blood volume was used.2
SILBERT S, KORNZWEIG AL, FRIEDLANDER M. THROMBO-ANGIITIS OBLITERANS (BUERGER): IV. REDUCTION OF BLOOD VOLUME. Arch Intern Med (Chic). 1930;45(6):948–957. doi:10.1001/archinte.1930.00140120123006
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