The comparative infrequency of primary carcinoma of the liver would seem to justify this report of nine such cases occurring at the Vancouver General Hospital during the years from 1920 to 1927, inclusive. During this period other cases occurred in which such a diagnosis was made, but these have been excluded from the present series either because of an incomplete autopsy or because the microscopic observations were open to question. The nine cases here reported are, we believe, undoubted instances of primary carcinoma of the liver.
At one time thought to be a common condition, true primary carcinoma of the liver is now known to be comparatively rare. Secondary involvement of the liver by metastasis from primary growths elsewhere, especially in the gastro-intestinal tract, is more common. No attempt will be made here to enter into any extensive discussion of the subject because of the excellent articles already available. In
G. F. STRONG, H. H. PITTS. PRIMARY CARCINOMA OF THE LIVER. Arch Intern Med (Chic). 1930;46(1):105–120. doi:10.1001/archinte.1930.00140130112008