Since Moebius1 in 1886 focused attention on the causative association of the thyroid with the disease which is now called hyperthyroidism, surgical intervention has become the almost universal therapeutic agent for relief from this condition. During the past fifty years the number of operative cases has increased enormously, yet there are surprisingly few accurate follow-up studies for determining what results thyroidectomy has produced on these patients. There is wide variation in the successful operative results reported in the relatively few postoperative studies. In a group of thyroidectomies reviewed one year later at the Lahey Clinic,2 it was claimed that cure was obtained in 92 per cent. In a series of cases which includes both exophthalmic and toxic adenoma, reported by Judd,3 it was stated that 65 per cent of the patients having severe hyperthyroidism were cured, while 80 per cent who had toxic adenoma were relieved from their toxic symptoms
CLARKE NE, BLACK I. POSTOPERATIVE RESULTS IN TOXIC GOITER. Arch Intern Med (Chic). 1930;46(2):266–282. doi:10.1001/archinte.1930.00140140104006
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