Seven years ago I suggested the theory that the undeniable influence that high altitude exercises on asthma and other allergic diseases is due to the absence of climate allergens in these regions. The correctness of this idea was proved by the demonstration of the fact that the effect that high altitude has on these diseases may be obtained in low-lying districts and in moist climates simply by technical methods, which involve the construction of a so-called allergen-proof chamber in the house of the patient. We have shown that "climate" in relation to allergic diseases is for the most part related to the condition of the soil, and that a moist soil with high absorbing power for water and a high level of ground water is unfavorable for patients with asthma, whereas a dry soil (sand, rock, chalk) with a low water capacity and a low level of ground water is
VAN LEEUWEN WS. PULMONARY TUBERCULOSIS: TREATMENT IN ALLERGEN-PROOF CHAMBERS. Arch Intern Med (Chic). 1930;46(4):637–643. doi:10.1001/archinte.1930.00140160087009
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