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Article
December 1930

THE ORIGIN OF UROBILINOGEN: A CLINICAL EXPERIMENT

Author Affiliations

MONTREAL, CANADA

From the Department of Metabolism, the Montreal General Hospital.

Arch Intern Med (Chic). 1930;46(6):1014-1017. doi:10.1001/archinte.1930.00140180115011
Abstract

From time to time physiologists devise various experimental procedures to test their theories. Occasionally, however, one may meet with a clinical condition that corresponds to the ideal laboratory experiment for explaining a given phenomenon. The literature contains many such examples, and the case reported here is an additional demonstration. Its data are of interest particularly with regard to the origin of urobilinogen in the body.

Estimation of the urobilinogen content of urine has now been a routine in this laboratory for a number of years, particularly in the study of disorders of the blood and liver. All methods available have been tried, but from a quantitative point of view none has been found perfect. For practical purposes, however, the method described by Wallace and Diamond in 1925, has been found to be the most satisfactory and has been in use since it was first reported. As in all laboratory tests

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