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Article
February 1931

DIFFERENTIAL DIAGNOSIS OF MEDIASTINAL "TUMORS": ANALYSIS OF EIGHT VERIFIED CASES

Author Affiliations

Senior Eugene Littauer Research Fellow in Pathology, Albany Medical College; Resident Physician, Albany Hospital ALBANY, N. Y.

From the Departments of Pathology and of Medicine, Albany Medical College and Albany Hospital.

Arch Intern Med (Chic). 1931;47(2):230-258. doi:10.1001/archinte.1931.00140200066006
Abstract

In 1888, Hare1 collected 520 cases of mediastinal disease, over 50 per cent of which were due to tumors, mostly of the malignant type. Riegel,2 Bennett,3 Eger,4 Harris5 and Steven6 have written monographs on the subject of intrathoracic and mediastinal tumors. Yet mediastinal tumors continue to awaken keen interest in view of their protean manifestations, their diagnostic difficulties and their generally poor prognosis. A review of the literature indicates that there is not a single pathognomonic symptom or sign on which one can depend in the differential diagnosis of mediastinal masses. As has been repeatedly shown, metastasis elsewhere in the body may initiate and dominate the symptomatology. The eight cases here reported originated in the anterior, middle or posterior mediastinum. We have had several cases of esophageal carcinoma, limited strictly to the posterior mediastinum, which we do not include in this report.

REPORT OF CASES  Case 1.—Malignant Endothelioma of the.

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