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Article
March 1931

GASTRIC ACIDITY IN DIABETES MELLITUS: ITS CLINICAL SIGNIFICANCE BASED ON A STUDY OF ONE HUNDRED CASES

Arch Intern Med (Chic). 1931;47(3):384-390. doi:10.1001/archinte.1931.00140210047004
Abstract

Persons with diabetes are exposed to all the conditions to which nondiabetic persons are exposed, infectious as well as noninfectious. For the diagnosis of some of these conditions, studies of gastric acidity are frequently employed. Such conditions include gastric and duodenal ulcers, disease of the gallbladder and hepatic disease in general, malignant conditions, anemias, etc. Therefore, it is important to know whether diabetes, per se, may be responsible for disturbances of gastric acidity.

Working with the same disease daily, one can hardly fail to be impressed by various phenomena as they are met with from time to time, and the impression gained was that in diabetes not only does the gastric acidity tend to be lower than normal, but achlorhydria occurs frequently. In the interpretation of these observations, there is, however, an important variable to consider. Determination of gastric acidity is not part of the routine in the management of

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