The syndrome described by Werner Schultz1 in 1922 and previously mentioned by Türk2 in 1907 has been reported frequently in the last three years. In 1927, Kastlin3 found forty-three cases in the literature. From June, 1927, to March, 1930, more than ninety cases were reported. The original syndrome described by Schultz as agranulocytosis and later named agranulocytic angina by Friedemann included an acute onset, usually in a woman, with a course marked by ulceration of the mouth or throat, leukopenia characterized by a considerable decrease or absence of granular cells and a normal red cell and platelet count, with death as the result. Some of the cases reported since do not coincide in all particulars with the syndrome originally described, since some occurred in males; in some there was involvement of the throat, and in some there were hemorrhagic tendencies; in some cases, the patients recovered. In this article the