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April 1931


Arch Intern Med (Chic). 1931;47(4):674. doi:10.1001/archinte.1931.00140220163013

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This little book opens with a concise historical sketch of the scientific work, from von Mehring and Minkowski to Banting and Collip, that led to the discovery and isolation of insulin. This is followed by a short discussion of the theories of the action of insulin and then by a practical exposition of the treatment for diabetes and its complications. Other chapters cover insulin therapy in the diabetes of children, resistance to insulin and complications attending the administration of insulin, especially the hypoglycemic reaction and edema caused by insulin. In a second section, critical consideration is given to the use of insulin in nondiabetic diseases, especally in cachexia and anorhexia, in parenchymatous lesions of the liver, in hyperthyroidism, in infections and in other conditions. While the reviewer, from personal experience, is inclined to be somewhat more critical than the author as to the value of insulin in nondiabetic diseases, he

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