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May 1931

Treatment of Epilepsy.

Arch Intern Med (Chic). 1931;47(5):826. doi:10.1001/archinte.1931.00140230153014

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The author has been concerned for some time with the careful and controlled therapy of epileptic patients. In this he has become proficient, because he has understood the modern conception of human metabolism and has applied his knowledge in an attempt to check what is, at least theoretically, a disturbance of metabolism. Dr. Talbot completely reviews the theories as to the etiology of epilepsy, and summarizes in an excellent manner present conceptions. He stresses, naturally, the theories of disturbance in oxygenation, the acidbase equilibrium and the water content. All of these factors may, of course, be part of one underlying disturbance. There does not seem to be enough evidence, however, that in the epileptic patient there is an excessive amount of hydration, a deficiency in oxygen or a tendency to alkalosis. The greatest evidence for these factors as a basis is the therapeutic effect of their reversal. Dr. Talbot considers

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