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The author's introduction points out the present difficulties in teaching therapeutics when he says: "The aim of the medical curriculum is to provide the student with sufficient knowledge to treat disease rationally; yet, as a rule, there is no part of his training with which the young graduate is more dissatisfied. He is taught Pharmacology and Therapeutics before he has had the opportunity of studying disease; he may even be instructed in therapeutics by one who, though possessing a medical degree, has not himself any experience in the practice of medicine. To some extent, no doubt, this is made good in the clinique, but it is too frequently the case that when the history and physical signs have been elicited, the diagnosis, differential diagnosis, and prognosis discussed, and the pathological aspect of the disease fully considered, the all important question of treatment is either ignored or is dealt with in