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Article
November 1931

INTESTINAL OXYGENATION IN IDIOPATHIC ULCERATIVE COLITIS: PRELIMINARY REPORT

Arch Intern Med (Chic). 1931;48(5_I):786-792. doi:10.1001/archinte.1931.00150050067005
Abstract

Prior to three years ago, the best results obtained in the treatment of patients with nonspecific ulcerative colitis coming under my observation centered about the use of colonic irrigations with strong oxidizing agents. Their possible effect on the tissues, the colonic flora or both was noted in a previous communication.1 While watching the progress of these cases, it occurred to me that perhaps pure oxygen in amounts sufficient to alter materially the gaseous tension in the intestines might prove more effective and less distressing than the fluid irrigation. The encouraging results obtained by the use of oxygen in idiopathic ulcerative colitis prompted this preliminary report.1a A final and detailed account of the laboratory and clinical investigations will be made at a future date. The present study comprises a total of 117 cases including control groups, fairly distributed so as to include all types of the disease. The entire

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