—Mrs. M. B., aged 28, a clerk, who was separated from her husband, complained that she had tired generally for years. The family history revealed that the mother had been invalided by a fall, and that the father had died of heart trouble. The patient's past history showed influenza, pertussis, measles, chickenpox and intermittent fever with an abscess under the chin. Several teeth had been filled, none of which was abscessed. She had been subject to tonsillitis, and a tonsillectomy had been performed three years before admission to the hospital. She had had slight colds and, ten years before, one attack of hemoptysis. During the past spring she had had a queer, dull, occipital ache, which had been constant for one week (she worked under electric light all day). On exercise and at other times, she had been faint, dizzy and short of breath. The pulse had been rapid.