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February 1932


Arch Intern Med (Chic). 1932;49(2):188-198. doi:10.1001/archinte.1932.00150090018003

The importance of the elevation of pulse rate and pulse pressure in the diagnosis of disturbances of the thyroid has long been recognized. Despite the importance of these symptoms and the fact that they are easily available to quantitative treatment, their clinical use is largely by rule of thumb. Since their value is so generally recognized by rule of thumb methods, it seems not unreasonable to suppose that it might be considerably increased by the application of more precise methods of study and use.

In 1924, Read published a formula for the prediction of basal metabolism from basal pulse rate and basal pulse pressure.1 The formula is 0.75 (pulse rate + 0.74 pulse pressure) — 72 = basal rate. Read stated that by this formula it was possible to predict the basal metabolic rate within 10 per cent in a little more than half of the cases.

Hunt compared basal rate