In a recently reported study of four hundred adults with asthma, 47 per cent were found to be insensitive to the usual soluble proteins. There was reason to believe that in this group the asthma was an expression of allergy accompanying infection resident in foci of the respiratory tract, in contradistinction to the other groups in which atopic hypersensitiveness, as well as infection, played a rôle. In the entire series of four hundred patients, there were nine in whom, in addition to asthma attacks of arthritis developed. The ages of these patients varied from 36 to 59. Six were females and three, males. The character of the arthritis was migratory, affecting the wrists, fingers, shoulders, ankles, etc. It was accompanied by moderate redness and swelling and pain on motion, and sometimes persisted for several weeks. The body temperature was not elevated. With the exception of three of our cases in
HARKAVY J, HEBALD S. ASSOCIATION OF INFECTIOUS ASTHMA AND ARTHRITIS FROM THE POINT OF VIEW OF BACTERIAL ALLERGY. Arch Intern Med (Chic). 1932;49(4):698–708. doi:10.1001/archinte.1932.00150110161009
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